Tranexamic Acid Wider Use

Tranexamic Acid Wider Use

Tranexamic Acid Wider Use is being considered for any procedure in which bleeding is expected. This is to reduce perioperative bleeding.

It is to be used for adults when anticipated blood loss exceeds 500mL. Children are also included if aged 1-15 years when expected loss exceeds 10% of blood volume. Safety data showed lower all-cause mortality and a reduced need for repeat operations. Thromboembolic events occurred in less than 0.1% of patients.

Other benefits included reduced postoperative pain, particularly for procedures involving small cavities, lower haematoma and infection rates, and earlier resumption of antiplatelet and anticoagulant medications.

Additional advantages not captured in economic models include improved visibility for surgeons due to less bleeding, decreased need for surgical drains, lower infection risk, and reduced post-operative bleeding.